Synthesis and evaluation of a desymmetrised synthetic lectin: An approach to carbohydrate receptors with improved versatility

Tiddo J. Mooibroek,* Matthew P. Crump and Anthony P. Davis*

Org. Biomol. Chem, 2016, 14, 1930-1933


A new synthetic lectin features apolar surfaces provided by two different aromatic components (biphenyl and pyrenyl). Affinities up to 260 M-1 are recorded for carbohydrates in water. The desymmetrised design has potential for variation to give receptors with a broadened range of capabilities.