Author Archives: richard.ren

Glucose-sensitive insulin with attenuation of hypoglycaemia

Thomas Hoeg-Jensen, Thomas Kruse, Christian L. Brand, Jeppe Sturis, Christian Fledelius, Peter K. Nielsen, Erica Nishimura, Alice R. Madsen, Lennart Lykke, Kim S. Halskov, Simona Koščová, Vladislav Kotek, Anthony P. Davis, Robert A. Tromans, Michael Tomsett, Guillem Peñuelas-Haro, Daniel J. Leonard, Michael G. Orchard, Andy Chapman, Gaetano Invernizzi, Eva Johansson, Daniele Granata, Bo F. Hansen, Thomas A. Pedersen, Jonas Kildegaard, Karen-Margrethe Pedersen, Hanne H. F. Refsgaard, Lene Alifrangis, Johannes J. Fels, Anita V. Neutzsky-Wulff, Per Sauerberg & Rita Slaaby

Nature. 634, 944-951 (2024)

Professor Davis awarded an ERC Advanced Grant

Tony will receive € 2.5 million funding for his project After GluHUT – A New Era for Synthetic Carbohydrate Receptors (POSTGLUHUT) which aims to transform the lives of diabetics.

Molecules which bind carbohydrates can have a range of medical uses. An important example is the application of glucose-binding molecules in glucose monitors for diabetics, and potentially in glucose-sensitive insulin which becomes more active as glucose levels increase. Our group recently developed a glucose-binding molecule called “GluHUT” (Glucose-binding Hexaurea Temple) which turns out to be remarkably effective. This ERC-funded project, “POSTGLUHUT”, aims to exploit GluHUT in a number of new ways, and also to develop the underlying science so that other carbohydrates can be targeted.

Congratulations Tony! More details can be found here: Bristol Chemistry

Congratulations to Dr. Claire Webster!

We are pleased to congratulate Claire on passing her viva lately. Clarie was a helpful senior student in the group and has started her career in a patent company in Southampton. We wish her having a good future and will miss her when having a Poutine in Colston😜.