Cationic cyclocholamides; toroidal facial amphiphiles with potential for anion transport

S. D. Whitmarsh, A. P. Redmond, V. Sgarlata, A. P. Davis*

Chem. Commun. 2008, 3669-3671


Cholic acid has been transformed into cyclotrimeric and cyclotetrameric toroidal amphiphiles with inward-directed ammonium substituents; the cyclotrimer 3b effects the transport of chloride anions across vesicle bilayer membranes.