Danny Van Eker, Soumen K. Samanta and Anthony P. Davis
Chem. Commun. 2020, 56, 9268-9271
Our design was selected for the front cover of this issue.
Abstract
A water-soluble bis-anthracenyl tetralactam binds biogenic heterocycles with high affinities in aqueous solution, rising to 107 M-1 for the purine hypoxanthine. Recognition occurs through a combination of hydrogen bonding and hydrophobic interactions, and results in fluorescence changes which suggest applications in sensing.