Thiourea isosteres as anion receptors and transmembrane transporters

M. Wenzel, M. E. Light, A. P. Davis, P. A. Gale*

Chem. Commun. 2011, 47, 7641-7643


Compounds containing cyanoguanidine and 3-amino-1,2,4-benzothiadiazine-1,1-dioxide have been studied as anion receptors and transporters. Significant affinity for oxo-anions was observed in organic solution and the receptors were found to function as transmembrane chloride/nitrate antiporters with transport rates enhanced in the presence of valinomycin–K+ complex.