Sterically geared tris-thioureas; transmembrane chloride transporters with unusual activity and accessibility

Hennie Valkenier,* Christopher M. Dias, Kathryn L. Porter Goff, Ondřej Jurček, Rakesh Puttreddy, Kari Rissanen and Anthony P. Davis*

Chem. Commun. 2015, 14235-14238.

Abstract

Tris-N-arylthioureas derived in one step from 1,3,5-tris(aminomethyl)-2,4,6-triethylbenzene are remarkably effective anion carriers. With optimised aryl substituents their activities come close to the best currently known, suggesting that they might find use as readily available standards in anion transport research.