Anion transport by ortho-phenylene bis-ureas across cell and vesicle membranes

Christopher M. Dias, Hongyu Li, Hennie Valkenier, Louise E. Karagiannidis, Philip A. Gale,* David N. Sheppard and Anthony P. Davis*

Org. Biomol. Chem. 2018, 16, 1083-1087.




Ortho-Phenylene bis-ureas serve as anionophores in cells expressing halide-sensitive yellow fluorescent protein, as well as in synthetic vesicles. Activities can reach high levels, and are strongly dependent on the deliverability of the transporters.